Impact of antiviral treatment and prevention programs on HCV transmission in rural Egypt

To control the epidemic in Egypt, the Ministry of Health and Population has strengthened infection control measures in healthcare facilities and initiated awareness and education campaigns. In addition, a comprehensive national treatment program was launched in 2008, with the opening of 23 centers providing fully subsidized antiviral treatment. The impact of these different measures on the HCV epidemic remains unknown.


The aim of this study was to compare the effectiveness of decreasing HCV iatrogenic transmission through mass treatment and prevention programs in a typical rural community of Egypt. Consequently, we developed a mathematical model describing HCV transmission in a typical rural community with average HCV seroprevalence. The model is calibrated using data collected in the Menofia governorate and data from the 2008 Demographic and Health Survey. Analyses are on-going and results will be available soon. This model could then be further used to simulate various implementation strategies of prevention programs. Particularly, we will evaluate the potential impact of (i) educating the general population, (ii) educating health care workers, and (iii) providing single-use material for health care interventions on decreasing incidence of iatrogenic transmission.


Note: This study has now been finished and results will be posted here soon


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fp7_01fp7_02 This project is funded
by the European Union