Inserm Unit U563, Toulouse

The Inserm Unit 563 or The Physiopathology Centre of Toulouse Purpan (CPTP) is a mixed Research Centre Inserm – University of Paul Sabatier. The collaboration between the diverse research teams is organised around 4 themes with a continuous flow of fundamental research into clinical research: mechanisms of oncogenesis and research for new therapeutic targets; signalling pathway and role of the lipid mediators; immunopathology and immuno-virology; genetics and gene therapy.



Prof Jacques Izopet and Dr. Florence Abravanel (Inserm Unit U563, “Viral infections: persistence, host response and pathophysiology”) study HIV pathophysiology under potent antiretroviral therapy and the HEV persistence in immunocompromised patients. They are also working on the variability of hepatitis viruses including HCV and HEV and its influence on the virus clearance.


Role in the collaboration

Prof Jacques Izopet is the reference virologist responsible for the quality control of PCR and other virologic tests. JI and FA participate in research on HCV, HBV and HEV conducted in Egypt.


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Introduction of Sofosbuvir in Egypt

In July 2014, Gilead and the Egyptian government signed an agreement for a treatment expansion of Sovaldi® (Sofosbuvir). Read more

Scientific Advisory Board Meeting

The Scientific Advisory Board Meeting was held in Paris February 15-16, 2013.

Read more

fp7_01fp7_02 This project is funded
by the European Union